Environment-insensitive fluorescent probes: A new class of bright and reliable molecular sensors

본 연구실에서 개발된 Environment-insensitive fluorescent probes에 대해 Research Features에 게재되었습니다.

Article URL:

https://researchfeatures.com/environment-insensitive-fluorescent-probes-new-class-bright-reliable-molecular-sensors/

Abstract:

Fluorescence imaging has established itself as the technique of choice among many biochemical and medical scientists for its high sensitivity and real-time detection capabilities. While fluorescent probes have contributed to advancing the knowledge of cell physiology and biological systems, their brightness can be affected by the medium. Dr Kyo Han Ahn from Pohang University of Science and Technology, South Korea, and Dr Yong Woong Jun at Stanford, USA, have developed exceptionally bright benzocoumarin fluorescent dyes. They revealed that the intracellular environment provides a unique space for the fluorophores, distinguished from those of organic and aqueous media.