51137483_2466503386754020_2368870778109165568_n (1)_edited_edited.jpg

Sourav Sarkar, PhD

Research Assistant Professor

Dept. of Chemistry, POSTECH

Postdoc (2020-2022) @ POSTECH, South Korea

PhD         (2015-2020) @ POSTECH, South Korea

MS           (2013-2015) @ IIT Kharagpur, India

BS            (2010-2013) @ University of Calcutta, India

Office  : #307 (Chemistry), POSTECH, South Korea

Phone : (+82) 054-279-5850

Email  : sourav@postech.ac.kr

Research interests

  • Probing redox molecules and enzymes

  • Environment insensitive dyes

  • Photoacoustic imaging

  • Imaging guided surgery

  • Organelle dynamics

  • Nucleic acid chemical biology

Expertise

  • Chemistry: Organic synthesis, Si-based nanomaterials, NMR, IR, LC-MS

  • Biophysics: ITC, CD, UV-Vis, fluorescence based spectrophotometric analysis

  • Biology: Electrophoresis, protein purification, cell culture, mice experiments (disease model)

  • Microscopy: CLSM, TPM, FLIM, IVIS

  • Theory: Matlab, Chemissian, Multiwfn, Gaussian’09

  • Tools: ChemDraw, Origin, MestReNova, Xcalibur, Leica, ImageJ, ImagePro, Discovery studio, Pymol, Autodock

Publications

1. Water-soluble pyrrolo[3,2-b]pyrroles: synthesis, luminescence and two-photon cellular imaging properties.

M Santra, YW Jun, J Bae,  S Sarkar, W Choi, DT Gryko, KH Ahn*. Asian J. Org. Chem. 2017, 6, 278.                                               [IF: 3.32]

2. Lavender violet, blue and pink: a new type of benzo[a]phenoxazine-based dipolar, red-emitting dyes.

M Santra, YW Jun, YJ Reo, S Sarkar, KH Ahn*. Dyes Pigm. 2017, 142, 161.                                                                                             [IF: 4.89]

3. A two-photon fluorescent probe for ratiometric imaging of hypochlorous acid in live cells and tissues.

YW Jun,† S Sarkar,† (†equal cont.) S Singha, YJ Reo et al. Chem. Commun. 2017, 53, 10800.                                                           [IF: 6.22]

4. Two-photon absorbing 8-hydroxy-benzo[g]coumarins with giant Stokes shifts: an environment-insensitive dye 

platform for probing biomolecules.
S Sarkar, M Santra, S Singha, YW Jun et al. J. Mater. Chem. B. 2018, 6, 4446.                                                                                      [IF: 6.33]

5. Dual probing of redox species, NAD(P)H and HOCl, with a benzo[a]phenoxazine-based far red-emitting dye.

M Santra, S Sarkar, YW Jun, YJ Reo, KH Ahn*. Tetrahedron Lett. 2018, 59, 3210.                                                                                [IF: 2.41]

6. Exploration of molecular shape-dependent luminescence behavior: fluorogenic organic nanoparticles based on

bent shaped excited-state intramolecular proton-transfer dyes.

M Santra, YW Jun, S Sarkar, YJ Reo, W Choi, JE Kwon et al. ACS Appl. Bio Mat. 2018, 1, 136.                                                         [IF: 3.25]

7. Molecular probes for fluorescence imaging of ATP in cells and tissues.

YW Jun, S Sarkar, KH Kim, KH Ahn*. ChemPhotoChem. 2019, 3, 1. (Invited article)                                                                           [IF: 3.85]

8. Ratiometric imaging of γ-glutamyl transpeptidase unperturbed by pH, polarity, and viscosity changes: a  benzo-

coumarin-based two-photon fluorescent probe.
YJ Reo, YW Jun,
S Sarkar, M Dai, KH Ahn*. Anal. Chem. 2019, 91, 14101.                                                                                              [IF: 6.99]

9. An endeavor in the reaction-based approach to fluorescent probes for bio-analytes: challenges & achievements.

S Singha, YW Jun, S Sarkar, KH Ahn*. Acc. Chem. Res. 2019, 52, 2571.                                                                                                  [IF: 22.4]

10. A rationally designed polarity–viscosity sensitive probe for imaging lipid droplets.

CW Song, U Tamima, YJ Reo, M Dai, S Sarkar, KH Ahn*. Dyes Pigm. 2019, 171, 107718.                                                                   [IF: 4.89]

11. Bent‐benzocoumarin dyes that fluoresce in solution and in solid state and their application to bioimaging.

M Dai, S Sarkar, CW Song, YJ Reo, YJ Yang, KH Ahn*. ChemPhotoChem. 2020, 4, 721.                                                                       [IF: 3.85]

12. A caveat to common hemicyanine dye components and their resolution.

HJ Park, CW Song, S Sarkar, YW Jun, YJ Reo, M Dai, KH Ahn*. Chem. Commun. 2020, 56, 7025.                                                    [IF: 6.22]

13. A systematic study on the discrepancy of fluorescence properties between in solutions and in cells: super-bright,

environment-insensitive benzocoumarin dyes.
YJ Reo, YW Jun, SW Cho, J Jeon, H Roh, S Singha,
S Sarkar et al. Chem. Commun. 2020, 56, 10556.                                            [IF: 6.22]

14. Study on hypoxia susceptibility of organ tissues by fluorescence imaging with a ratiometric NTR probe.

S Sarkar, H Lee, HG Ryu, S Singha et al. ACS Sens. 2021, 6, 148.                                                                                                              [IF: 7.71]

15. Imidazolyl–benzocoumarins as ratiometric fluorescence probes for biologically extreme acidity.

H Kim,† S Sarkar,† (†equal cont.) et al. Spectrochim Acta, A. 2021, 248, 119088. (Invited article)                                                 [IF: 4.09]

16. Structurally compact, blue–green–red fluorescence trackers for the outer cell membrane: zwitterionic (naphthylvinyl) pyridinium dyes.

YJ Reo, S Sarkar, M Dai, YJ Yang, KH Ahn*. ACS Appl. Bio Mater. 2021, 4, 2089. (Invited article)                                                    [IF: 3.25]

17. Electronic effects on the depropargylation process in the reaction‐based fluorescent detection of palladium species: benzocoumarin‐based ratiometric sensing systems.
SW Cho, YJ Reo,
S Sarkar, KH Ahn*. Bull Korean Chem Soc. 2021, 42, 135. (Invited article)                                                            [IF: 0.97]

18. Environment-insensitive two-photon ratiometric probe for in cellulo quantitative measurement of H2O2.

SW Cho, YW Jun, YJ Reo, S Sarkar, KH Ahn. Results in Chemistry 2021, 3, 100117. (Invited article)                                             [IF: 0.00]

19. NAD(P)H quinone oxidoreductase-1 in organ and tumor tissues: distinct activity levels observed with a benzorosol-based dual-excitation and dual-emission probe.
YJ Yang, M Dai, YJ Reo, CW Song,
S Sarkar, KH Ahn*. Anal. Chem. 2021, 93, 7523.                                                                             [IF: 6.99]

20. A rationally designed two-photon ratiometric elastase probe for investigating inflammatory bowel disease.

S Sarkar,* A Shil, M Nandy, S Singha et al. Anal. Chem. 2022, 94, 2, 1373–1381                                                                                   [IF: 6.99]

21. Pi-stacking-based fluorescent probe for labeling of flavin analogues in live cells through unusual FRET process.

S Biswas, S Sarkar,* A Shil, T Demina et al. Anal. Chem. 2022, 94, 8, 3494–3500                                                                              [IF: 6.99]

22. A two-photon, ratiometric sensing platform based on a solid-state luminescent benzocoumarin: Application to prolonged bioimaging of hydrogen peroxide.

H R Kim,† S Sarkar,† (†equal cont.) K H Ahn*. Chem. Asian J. 202217, e2021013                                                                             [IF: 4.57]

Academic responsibilities

  • Reviewer @ Sensors & actuators B ll Cancer ll Molecules ll Chemosensors ll New Journal of Chemistry

  • Guest editor @ Cells: Special issue on “Fluorescent materials for bio-relevant applications”.

Social responsibilities

  • Founder, Iccha Foundation.                                                                                                                                                                    [2018-till date]

  • President, POSTECH Graduate Students’ Association (GSA).                                                                                                           [2018-2020]

  • President, POSTECH Student Ambassador (PSA).                                                                                                                                [2017-2018]

  • Governing body, ‘Uttoran’- An Endeavour.                                                                                                                                              [2013-2019]

  • Facebook
  • Twitter
  • LinkedIn
  • iccha foundation